A boy and girl - aged 12 and 14 - were arrested after a man aged in his 50s was attacked near a bus station.
The victim, 51, was taken to hospital as a result.
Police said an 'argument' broke out between a group of youngster and the man near the bus station in Congleton town centre on Saturday night.
Detectives are appealing for witnesses.
The man, who hasn't been named, was taken to hospital to be assessed.
An investigation is ongoing.
In a statement, Cheshire Police said: "Police are appealing for witnesses following an altercation in Congleton town centre.
"At around 7.30pm on Saturday, an argument broke out between a number of young people and a 51-year-old man.
"The man was then assaulted near the bus station. He was taken to hospital to be assessed.
"As part of the enquiries into the assault, a 14-year-old girl and a 12-year-old boy have been arrested. An investigation is ongoing."
Det Con Lee Ferris said: "At this time of evening, the town centre would have been pretty busy.
"I'd urge anyone who witnessed the incident, or has dash cam footage that may help to contact us.
"We have increased patrols in the area to provide reassurance and would urge anyone with information to contact us to help us progress our investigation."
No further details have been revealed.
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